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China approves first-ever drug for acute mountain sickness prevention_我的网站
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China has granted marketing approval of its first drug for the prevention of acute mountain sickness, filling the long-standing gap in the domestic market where no such medications had been available, Science and Technology Daily reported on Tuesday.
The National Medical Products Administration (NMPA) has approved the marketing of acetazolamide sustained-release capsules, the report said. As the first specialized drug in China indicated for preventing of acute mountain sickness, its approval marks the end of the country's lack of dedicated preventive treatment for altitude illness.
By inhibiting the activity of carbonic anhydrase, acetazolamide promotes the renal excretion of bicarbonate, corrects respiratory alkalosis caused by hypoxia at high altitudes, thereby regulating acid-base balance, optimizing respiratory status, elevating blood oxygen levels, and reducing the risk of onset at the source.
In contrast to health products that only provide auxiliary regulatory effects, this medication has been validated through stringent clinical trials and stands as a specialized drug approved by the NMPA with a clear indication for prevention, said the report.
Led by principal investigator is Luobu Gesang, a deputy dean of the People's Hospital of Xizang Autonomous Region, the clinical trial was designed by his team and has yielded critical evidence to inform prevention strategies for altitude sickness that are specifically adapted to Chinese and Asian populations.
"Previously, although acetazolamide had already been used internationally for the prevention of acute mountain sickness, China had long lacked an NMPA-approved acetazolamide formulation supported by rigorous clinical trials. Furthermore, the existing international formulations were short-acting tablets requiring multiple daily doses, and no drugs with the relevant indication were available on the domestic market for an extended period," said Luobu Gesang.
The sustained-release capsule approved this time not only fills this critical gap but also optimizes the dosage form, providing more reliable and convenient medication protection for the physical health and life safety of people entering high-altitude areas, he added.
Clinical trials showed that, compared with the placebo group, the incidence of acute mountain sickness in the medication group was significantly reduced, with the incidence of moderate-to-severe acute mountain sickness decreasing by 14.6 percent, according to the report.
Related research has been published in the international flagship journal of high-altitude medicine, High Altitude Medicine & Biology.
Global Times
。 Kakao Games于今日（8月20日）在首尔举办了2.5D MMORPG《鬼怪世界》媒体展示会，正式公布游戏将于10月上线，并于今日同步开启预注册。
关于《鬼怪世界》《鬼怪世界》是一款以韩国传统民间传说为基础的东方奇幻MMORPG，采用2D像素角色与3D背景相结合的2.5D混合图形技术。游戏基于Naver人气网络小说及网络漫画《灭鬼修道传》IP开发，由《我独自升级》制作方Redice Studio参与合作，共同构建K- fantasy世界观。游戏故事设定在原作时间的300年前，无论是原作粉丝还是新玩家都能享受全新的叙事体验。
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从《风之王国：燕》到《鬼怪世界》，Supercat在像素图形领域的积累终于迎来了一次风格上的转向，从三国到韩国民俗，从写实到像素。10月上线后，这套无职业的技能组合系统能不能真的跑通，到时便知分晓。
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Published on:07:20:55